Methotrexate FDA Link Generic

An antineoplastic antimetabolite with immunosuppressant properties. It is an inhibitor of TETRAHYDROFOLATE DEHYDROGENASE and prevents the formation of tetrahydrofolate, necessary for synthesis of thymidylate, an essential component of DNA.

Also Known As:

Mexate; Methotrexate Hydrate; Methotrexate Sodium; Methotrexate, (D)-Isomer; Methotrexate, (DL)-Isomer; Methotrexate, Dicesium Salt; Methotrexate, Disodium Salt; Methotrexate, Sodium Salt; Dicesium Salt Methotrexate; Hydrate, Methotrexate; Sodium, Methotrexate; Amethopterin; L-Glutamic acid, N- (4- (((2,4- diamino- 6- pteridinyl)methyl)methylamino)benzoyl)-

Pharmalogical Action Categories:

Abortifacient Agents, Nonsteroidal
Antimetabolites, Antineoplastic
Antirheumatic Agents
Dermatologic Agents
Enzyme Inhibitors
Folic Acid Antagonists
Immunosuppressive Agents
Nucleic Acid Synthesis Inhibitors

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Pteridines: 147
      - Pterins: 160
        Aminopterin: 248
        Methotrexate: 24010

F Hurley Selected Research

F Hurley Research Topics

Disease

Drug/Important Bio-Agent (IBA)